older antihistamines have strong **anticholinergic** effects.
These medications block acetylcholine, a chemical involved in memory, attention, and other brain functions. The National Institute on Aging specifically identifies antihistamines among medicines that can impair cognition in older adults.
Strong anticholinergic medications have also been associated with a higher risk of dementia in observational research, particularly with greater cumulative exposure. This association does not prove that the drugs directly cause dementia, but it is one reason long-term use deserves review.
## 4. Some Bladder Medications
Certain medications used for overactive bladder also have
