negative effects on the kidneys or the cardiovascular system, even in participants with blood vitamin D levels reaching 100 nmol/L.
For comparison, a 2017 study analyzed the effects of a level of 300 nmol/L, corresponding to a daily intake of 15,000 IU. It concluded that these levels, although very rare, did not present any significant danger.
True cases of vitamin D toxicity are exceptional and generally occur at blood concentrations above 375 nmol/L. This threshold corresponds to a daily intake of approximately 50,000 IU for