increase the chance of kidney strain when used regularly. Salt substitutes that contain potassium should be discussed with your doctor if you take losartan or valsartan, as they can raise potassium levels further. Grapefruit juice may increase the blood levels of amlodipine in some people, so limiting or avoiding it is often recommended. Alcohol can enhance the blood-pressure-lowering effect of any of these drugs and raise the chance of dizziness.
Dehydration from illness, heat, or not drinking enough fluids can affect kidney function more noticeably when you’re on an ARB.