If cholesterol-related plaque builds up in the arteries that supply the heart, blood flow can become limited. This can lead to chest pain or pressure, also called angina. Mayo Clinic explains that atherosclerosis in heart arteries may cause chest pain or pressure.
Chest discomfort may feel like heaviness, squeezing, burning, tightness, or pressure. It may happen during activity, stress, or after a heavy meal, and sometimes improves with rest.
Chest pain should always be taken seriously, especially if it is new, severe, or comes with shortness of breath, sweating, nausea,
